CD34+ cells are multipotent and can give rise to all cell types in blood. CD34+ cells are most known for their expression on hematopoietic stem cells found in the bone marrow and cord blood, but are also found circulating in peripheral blood.
CD34+ cells are responsible for all lymphohematopoietic lineages and are now commonly used clinically as they have been shown to provide long-term durable donor-derived host lymphohematopoietic reconstitution.
Human CD34+ Hematopoietic Stem Cells (HSCs)
Our CD34+ cells are collected at FDA-licensed donor centers from healthy human donors and further processed at our cell isolation laboratory. CD34+ cells are isolated from peripheral blood mononuclear cells using immunomagnetic cell isolation. These represent the cells that repopulate the hematopoietic system following transplantation. This treatment stimulates CD34+ cells and other immature cells to move into the circulation where they can easily be collected. We isolate CD34+ cells by positive immunomagnetic selection, and each product is characterized by flow cytometry to ensure a highly pure and viable cell population. Try these in your studies of hematopoietic cell differentiation.
All donors are tested for HIV, Hepatitis B and C, WNV, CMV, and other blood-borne pathogens.
Biospecimens are obtained from properly consented donors. We conform to HIPAA standards to protect the privacy of the donor’s personal health information.
Human Material Precaution
It is best to use caution when handling any human cells. We recommend all human cells should be handled as if potentially infectious following biosafety level 2 procedures.
Even with infectious virus assays or viral antigen assays, a negative test result may leave open the possible existence of latent viruses.