Memory CD8+ T cells are a subset that respond to cognate antigens (Ag) and persist long-term. Memory CD8+ T cells provide immune-mediated protection against solid tumors and infection from intracellular bacteria, viruses, and parasites. Compared to naïve CD8+ T cells, memory CD8+ T cells persist in greater numbers and are poised to immediately proliferate, execute cytotoxic functions, and secrete effector cytokines upon Ag re-encounter.
Memory CD8+ T cells
Our memory CD8+ T cells are collected at FDA-licensed donor centers and further processed at our cell isolation laboratory. Memory CD8+ T cells are isolated from PBMCs using negative immunomagnetic cell separation procedures. Each product is characterized by flow cytometry to ensure a highly pure and viable cell population. All donors are tested for HIV, Hepatitis B and C, WNV, CMV, and other blood-borne pathogens.
All biospecimens are obtained from properly consented donors. We conform to HIPAA standards to protect the privacy of the donor’s personal health information.
Human Material Precaution
It is best to use caution when handling any human cells. We recommend all human cells should be handled as if potentially infectious following biosafety level 2 procedures.
Even with infectious virus assays or viral antigen assays, a negative test result may leave open the possible existence of latent viruses.
