Naïve CD8+ T cells are mature T cells that have yet to be exposed to an antigen presented on the MHC class I molecule of an antigen-presenting cell (APC). They are considered mature but inactivated, responding to novel pathogens in the immune system. Once activated, CD8+ T cells defend the body against intracellular pathogens, such as viruses and bacteria, as well as cancerous cells by releasing cytotoxins that result in apoptosis of the infected or diseased cell.
Naïve CD4+ T cells
Our naïve CD8+ T cells are collected at FDA-licensed donor centers and further processed at our cell isolation laboratory. Naïve CD8+ T cells are enriched in a multi-step process by means of negative and positive selection. Each product is characterized by flow cytometry to ensure a highly pure and viable cell population. All donors are tested for HIV, Hepatitis B and C, WNV, CMV, and other blood-borne pathogens.
All biospecimens are obtained from properly consented donors. We conform to HIPAA standards to protect the privacy of the donor’s personal health information.
Human Material Precaution
It is best to use caution when handling any human cells. We recommend all human cells should be handled as if potentially infectious following biosafety level 2 procedures.
Even with infectious virus assays or viral antigen assays, a negative test result may leave open the possible existence of latent viruses.