Peripheral blood mononuclear cells (PBMCs) include lymphocytes, monocytes and dendritic cells and can be used in a variety of cell-based assays. PBMCs are critical for immunology research and clinical applications such as cell therapy and vaccine development due to their ability to provide valuable insights into immune responses in humans.
The objective of this eBook is to provide a quick reference resource to scientists who need to isolate and culture PBMCs or develop assays to study their function. Research scientists transitioning from animal to human studies could find this to be a particularly useful reference.
Given how valuable PBMCs are to research, it’s important for scientists to have a thorough understanding of the development, function and activation processes of each cell type. This eBook contains summaries on the following:
- Basic biology and function of each PBMC subset
- Lymphocyte activation processes
- Frequency of each cell type in peripheral blood
- Recent advances in immunotherapies involving PBMCs
Interested in an Easier Way to Source PBMCs?
PBMC isolation is a critical step in the preparation of human immune cells for use in downstream research assays and applications. Donor recruitment, sample collection, and cell isolation and cryopreservation are tedious and time-consuming processes. Many researchers work with human specimen suppliers like Cytologics as a fast and cost-effective way to source PBMCs. Our validated methods and quality control procedures ensure you’ll receive high quality cells resulting in minimal variability in your experimental protocols.